Frontiers in Research of the Renin-Angiotensin System on Human Disease - Proteases in Biology and Disease

Marc Notes: Includes bibliographical references and index. Table of Contents: Corresponding Authors; Preface; 1: Role of ACE, ACE2 and Neprilysin in the kidney, Mark C. Chappell; 2: ACE Inhibition in Heart Failure and Ischaemic Heart Disease, D. John Campbell; 3: Proteases of the Renin-Angiotensin System in Human Acute Pancreatitis, R. Pezzilli and L. Fantini; 4: The Renin-Angiotensin System in Pancreatic Stellate Cells: Implications in the Development and Progression of Type 2 Diabetes Mellitus, Seung-Hyun Ko, Yu-Bai Ahn, Ki-Ho Song and Kun-Ho Yoon; 5: Renin-Angiotensin System Proteases and the Cardiometabolic Syndrome: Pathopjysiological, Clinical and Therapeutic Implications, Guido Lastra, Camila Manrique and James R. Sowers; 6: The Role of the Renin-Angiotensin System in Hepatic Fibrosis, J. S. Lubel, F. J. Warner and P. W. Angus; 7: The Renin-Angiotensin System in the Breast, Gavin P. Vinson, Stewart Barker, John R. Puddefoot and Massoumeh Tahmasebi; 8: Role of Local Renin-Angiotensin System in the Carotid Body and in Diseases, Man Lung Fung and Po Sing Leung; 9: Bone Homeostasis: An Emerging Role for the Renin-Angiotensin System, C. Serina, H. Huang, K. Nguyen, L. Li, S. Hsu, M. Chen, N. Yu and M. Forwood; 10: The Renin-Angiotensin System and its Inhibitors in Human Cancers, Lucienne Juillerat-Jeanneret; 11: The Skeletal Muscle RAS in Health and Disease, David R. Woods; 12: Local Angiotensin Generation and AT2 Receptor Activation, Joep H. M. van Esch and A. H. Jan Danser; 13: ADAMs as Mediators of Angiotensin II Actions, A. M. Bourne and W. G. Thomas; IndexPublisher Marketing: The significant impact of the renin-angiotensin system (RAS) on basic research and its clinical relevance are reflected by the flourishing publication of original and review research articles; by the appearance of whole issues of journals dedicated to the RAS; and by specialist books on the RAS. In such a rapidly evolving environment, publications that span the spectrum from basic research to the bedside, fill a particularly valuable niche for clinicians and researchers alike. The primary aim of this book is to provide a topical and timely forum for the critical appraisal of an area of RAS research that is expanding rapidly. In this respect, a collection of thirteen chapters from distinguished and world-class experts in the field has been presented on the contemporary research of the RAS and their implications in human disease.