Studies on Redox Behaviour of Some Pharmaceuticals: Electrochemical Determination of Pharmaceuticals

Analytical Chemistry plays a critical role in the development of a compound from its synthesis stage to its marketing stage as a part of a drug formulation and analysis. The instrumental methods for quantitation which are most commonly used in a pharmaceutical laboratory fall into four basic categories: chromatography, spectrophotometric, electrochemical, and radiometric analysis. Electro-analytical chemistry along with the use of oxidation?reduction reactions and other charge-transfer phenomena had its origins eight decades ago. It is one of the fundamental sub-disciplines of analytical chemistry. Electrochemistry has always provided analytical techniques characterized by instrumental simplicity, moderate cost and portability. Electro-analytical techniques can easily be adopted to solve many problems of pharmaceutical interest with a high degree of accuracy, precision, sensitivity and selectivity, often in spectacularly reproducible way by employing this approach. Most of the pharmaceutical active compounds were found to be as an electrochemically active. Modern electrochemical methods are now sensitive, selective, rapid and easy techniques applicable to analysis in the drugs.