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Systems Biology: The Challenge of Complexity 2009 edition
Shigetada Nakanishi
Systems Biology: The Challenge of Complexity 2009 edition
Shigetada Nakanishi
Instead of reductionistic analyses or large-scale studies of biomolecules piece by piece, systems biology emphasizes the need for interdisciplinary methods and analysis of the regulation and operation of information networks at the systems level.
Marc Notes: The Uehara Memorial Foundation Symposium-2008--Cover.; Proceedings of a symposium of the same name held in Tokyo from June 30 to July 2, 2008.; Includes bibliographical references and index. Table of Contents: Preface -- Contributors -- Part I. Dynamics and Complexity of Intercellular Networks -- Integrative Synaptic Mechanisms of the Neural Network / Shigetada Nakanishi -- The Molecular and Cellular Design of Networks in Motion / Sten Grillner, Peter Wallen, Russell Hill -- Bacterial Complexity: More Is Different on All Levels / Eshel Ben-Jacob -- How Animals Get Their Skin Patterns: Fish Pigment Pattern as a Live Turing Wave / Shigeru Kondo -- Characterization and Application of Natural Light-Sensitive Proteins / Jens Looser, Georg Nagel -- Systems Biology of Mammalian Circadian Clocks / Hiroki R. Ueda -- Toward Understanding How the Immune System Establishes a Diverse Yet Self-Tolerant T-Cell Repertoire: Stepwise Roles of Thymic Microenvironments / Takeshi Nitta, Yousuke Takahama -- The Mechanisms of Motor Programming for Learned Vocalization in Songbirds / Hisataka Fujimoto, Taku Hasegawa, Ryosuke Matsui, Kentaro Abe, Dai Watanabe -- Dynamic Model of the Basal Ganglia Functions and Movement Disorders / Atsushi Nambu -- Part II. Integrative Mechanism of Intracellular Information Networks -- A Posttranslational Chemical Circadian Oscillator in Cyanobacteria / Hideo Iwasaki -- The Apoptotic Signaling Network Dynamically Interprets the Outputs of Individual Signaling Pathways in an Early Analog and Late Digital Manner / Kevin A. Janes, H. Christian Reinhardt, Michael B. Yaffe -- Specific Features of Transient Ras and Sustained Rap1 Activation / Yu-ichi Ozaki, Shinsuke Uda, Shinya Kuroda -- Control and Alteration of Protein Traffic in the Cell / Toshiya Endo -- Plant Functional Genomics Based on Integration of Metabolomics and Transcriptomics: Toward Plant Systems Biology / Kazuki Saito -- A Possible Role of Homeostasis Between Monomeric and Filamentous Actin in Filament Nucleation Revealed by Pharmacokinetic Modeling / Naoki Watanabe, Chiharu Higashida -- Molecules, Networks, and Memory / Upinder S. Bhalla -- Systems Biology Meets Single-Cell Physiology: Role of a Positive-Feedback Signal Transduction Network in Cerebellar Long-Term Synaptic Depression / Keiko Tanaka, George J. Augustine -- Computational Models of Cerebellar Long-Term Memory / Hideaki Ogasawara, Mitsuo Kawato -- Biogenesis and Function Mechanisms of Micro-RNAs and Their Role as Oncogenes and Tumor Suppressors / Soken Tsuchiya, Kazuya Terasawa, Ryo Kunimoto, Yasushi Okuno, Fumiaki Sato, Kazuharu Shimizu, Gozoh Tsujimoto -- Part III. Dysfunction of Information Networks and Related Diseases -- The Pathogenetic Significance of Deregulated Transcription Factors in Hematological Malignancies / Masahiro Nakagawa, Susumu Goyama, Motoshi Ichikawa, Mineo Kurokawa -- Ultradian Oscillation Networks in Somite Segmentation and Other Biological Events / Yasutaka Niwa, Hiromi Shimojo, Ryoichiro Kageyama -- The Cellular Basis of Dictyostelium Morphogenesis / Cornelis J. Weijer -- Metabolic Information Highway: Interorgan Metabolic Communication Via the Autonomic Nervous System / Hideki Katagiri -- Involvement of the CCR4-NOT Deadenylase Complex in the Control of Cell Growth / Masahiro Morita, Kentaro Ito, Toru Suzuki, Tadashi Yamamoto -- Reconstruction of Nuclear Reprogramming by Defined Factors / Shinya Yamanaka -- Index.
Media | Books Hardcover Book (Book with hard spine and cover) |
Released | April 17, 2009 |
ISBN13 | 9784431877035 |
Publishers | Springer Verlag, Japan |
Pages | 246 |
Dimensions | 155 × 235 × 15 mm · 566 g |
Editor | Kageyama, Ryoichiro |
Editor | Nakanishi, Shigetada |
Editor | Watanabe, Dai |
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